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Retatrutide does not yet have dedicated cardiovascular or renal outcome trials, though Phase 3 studies evaluating these endpoints are currently enrolling participants with expected completion in 2026

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FIGURE 5 GHK Increases miR-146a-3p Levels Through the PI3K/Akt Pathway and miR-146a-3p Inhibitor Reverses GHK-induced AQP4 Reduction in Astrocytes

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