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Before starting GLP-1 therapy Get comprehensive baseline blood work including ferritin, vitamin D, zinc, B12, thyroid panel (TSH, free T3, free T4), and a complete blood count

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The simultaneous activation of autophagy triggered by intracellular stress, such as endoplasmic reticulum stress and blockage of autophagic flux, can cause the accumulation of defective lysosomes

doi: 10.1016/j.knee.2021.03.009
