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Description
confirmed that TFAP2C regulated GPx1 expression by directly binding to the GPx1 promoter, which contains an AP-2 regulatory region, and the methylation of the CpG island in the GPx1 promoter region prevented the binding of TFAP2C by encompassing the AP-2 regulatory region [81]

A study comparing existing anti-SaCas9 and anti-SpCas9 antibodies in serum and vitreous fluid from 13 patients who underwent vitrectomy surgery found that all three serum samples tested positive for SaCas9 and SpCas9, whereas only two vitreous fluid samples were positive for SaCas9, and two others for SpCas9

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