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Reports 39 (11)

The major disadvantages of the aqueous liquid formulations are microbial contamination, chemical instability of the dissolved drug in aqueous conditions, presence of preservatives that may cause mucosal irritation, and short residence time in the nasal cavity due to mucociliary action [21]

Because stomach acid is required for the release of vitamin B 12 from the proteins in food, vitamin B 12 absorption is diminished

Due to the distinct position of the conjugated N-terminal lipid between Cagri-CTR and Cagri-AMY 1 R, we also determined a structure of CTR-Gs in complex with an analogue of Cagri that lacked the lipid modification (CagriBB) to interrogate the contribution of the acylation to the conformation of Cagri-CTR complex