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These receptor proteins are characterized by the presence of LIR motifs for the interaction with ATG8 family proteins such as LC3 on the surface of phagophores, and many have ubiquitin-binding domains capable of recognizing ubiquitinated cargo, thus establishing a bridge between the cargo and the autophagic machinery (40, 92, 93)

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Parenteral administration of vitamin B12 effectively and promptly replenishes B12 stores

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Mice lacking G0S2 are lean and cold-tolerant

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B12 plays a role in energy production by assisting in the metabolism of fats and proteins

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