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South Africa is one of three countries on the African continent that regulates the use of skin bleaching products, having banned harmful ingredients including mercury, hydroquinine and corticosteroids, and discriminatory cosmetic advertisements that claim to bleach, lighten or whiten skin

In contrast, in diseases characterised by mitochondrial dysfunction and bioenergetic failure (often reflected by reduced FDG-PET signal), elevated iron may instead represent a compensatory response to functional iron deficiency rather than a pathogenic surplus

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