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XML reduced Beclin 1 and Atg7 accumulation, upregulated protein kinase B (PKB)/Akt, PI3K, and Bcl-2 levels, and inhibited autophagy to alleviate cardiomyopathy (146) (Figure 5)

For example, in healthy adults weighing 70 kg, plasma level ranging from 10 to 30 mg/dL inhibits delta-aminolevulinic acid synthase (-ALAS), -aminolevulinic acid dehydratase (-ALAD), coproporphyrinogen decarboxylase, ferrochelatase and pyrimidine 5-nucleotidase ( Figure 1 )

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