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J Reprod Fertil 73 , 317321 (1985)
However, long-term use should be part of a mindful routine
More importantly, animal studies have corroborated that continuous or low-intensity nighttime light significantly suppresses the rhythmic expression of clock genes, including Per1 , Per2 , and Nr1d1 , within the SCN, thereby disrupting hormone secretion and metabolic status through effects on the downstream endocrine axis (81, 83)
Acknowledgments This work was supported by National Institutes of Health grants R01 AG057381 and R01 AG057381 (Ladiges PI)
