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doi: 10.3389/fendo.2020.608428 Received 20 September 2020 Accepted 08 December 2020 Published 26 January 2021 Volume 11 - 2020 Edited by Ilaria Muller, Fondazione IRCCS Ospedale Ca Granda Maggiore Policlinico, Italy Reviewed by Giampaolo Papi, Local Health Unit of Modena, Italy
It's a tripeptide that readily forms a complex with copper, and this copper-bound form is what we typically refer to as GHK-Cu

People with naturally higher melanin production may see minimal changes, while those with lighter baseline skin tones might notice more apparent effects

10.1210/en.131.5.2271