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Neither compound has established long-term human safety data

Based on class data from the tirzepatide SmPC, GLP-1 and GIP-based therapies may reduce oral contraceptive exposure during initiation and dose escalation

Identification, cloning, expression, and purification of three novel human calcium- independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

In a follow-up study, the same authors used contrast enhanced ultrasound to demonstrate that the age-related reductions in insulin-mediated MPS was associated with reductions in nutritive blood flow [25]