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The TGF- pathway has biphasic effects and acts as a tumor suppressor at early stages but later stimulates cancer progression by impacting tumor cells and their microenvironment [135]

Free radicals in biology and medicine, vol 5

ALA can also inhibit the release of tumor necrosis factor-, interleukin (IL)-6, and IL-1 into the serum and suppress the expression of inducible nitric oxide synthase [22] in septic AKI