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Functional studies have further demonstrated that MFAP2 knockdown suppresses tumor growth and is positively correlated with regulatory T cells (Tregs) and immune checkpoints such as CTLA4 and TIGIT, highlighting its potential as a prognostic biomarker and therapeutic target

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In IDH-mutant gliomas, studies have observed an increase in mtDNA copy number, whereas no significant changes were found in recurrent cancers [197]

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Among the many neurotrophins that regulate dendritic development, BDNF plays a crucial role in modulating dendritic length and complexity via the MAPK and CREB signaling pathways [83]

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BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide, consisting of 15 amino acid units, extracted from a fragment of a protective protein contained in human gastric juice

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