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Description
They reported that there is an overproduction of TNF- in obese rats and that neutralization of TNF- leads to increased glucose uptake in response to insulin

J Neurosci Methods 229:1527

Doses used clinically generally start modestly and can be adjusted upward based on the patient, with the intravenous route favored precisely because it sidesteps the oral-absorption question

DD drawings are design development drawings
