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The temptation to escalate the dose because nothing is happening yet is exactly the mistake the timeline section is designed to head off the mechanism is cumulative, not dose-chased
The MHRA ( Medicines and Healthcare products Regulatory Agency ) has two main application procedures: Simple Reclassification : This is a straightforward and quick procedure based on an analogous product (a medicinal product already on the UK market with the same active ingredient, route of administration, use, and a similar or higher strength/dosage)
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