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Aging, smoking, infection, genetic predisposition, abnormal biomechanical loading (such as long-term bending or heavy lifting), and reduced nutrient supply through the cartilage endplate are all inducing factors (Wu et al., 2021)

doi:10.1007/s00403-016-1710-3

Furthermore, advanced imaging and monitoring techniques are not available in smaller trauma care centers, making clinical management of patients with severe TBI even more difficult

Retatrutide holds value in obesity research due to its ability to significantly reduce fat mass while maintaining lean tissue
