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In another study, chlorophyllin treatment has been reported to cause cell cycle arrest in HCT116 colon cancer cells through the increased expression of E2F1 and E2F4 transcription factors inhibiting the G1/S checkpoint step, which is an important cell cycle checkpoint (Chimploy et al

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However, while some studies affirm these benefits, the findings are not universally consistent, indicating the need for further research

[DOI] [PubMed] [Google Scholar] [55].Olivieri G, Baysang G, Meier F, Muller-Spahn F, Stahelin HB, Brockhaus M, Brack C
