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Strains of cyanobacterial genera including Scytonema and Oscillatoria produced intracellular EGT at levels of up to 0.8 mg/g dry cells, which was higher than the levels found in king oyster mushrooms (Pfeiffer et al

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Key challenges for clinical translation include the lack of consistent benefit, as large RCTs and systematic meta-analyses have failed to demonstrate efficacy of prebiotics/probiotics in ICU patients despite encouraging signals in individual studies (Lee et al., 2023)

The provision of various bioactive factors, including but not limited to lactoferrin, lysozyme, leukocytes, immunoglobulins, cytokines, hormones, stem cells, breast milk oligosaccharides, microRNAs, antioxidants and growth factors plays a vital role in strengthening the babys immune system [11, 12]