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Indeed, injury to the brain in children and/or infants can be particularly devastating because it is superimposed on the precisely orchestrated and energy demanding processes required for brain development [134]

At the pathophysiological level, it is now clear that most narcolepsy cases with cataplexy, and a minority of cases (530 %) without cataplexy or with atypical cataplexy-like symptoms, are caused by a lack of hypocretin (orexin) of likely an autoimmune origin

Nov 12 2025;45(46)doi:10.1523/JNEUROSCI.1377-25.2025 Yang X, Yang B, Ming M, et al

Subsequently, growth experiments on carnitine containing minimal medium were initiated using different strains of E