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Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients

Although CPT1A and CPT1B exhibit considerable sequence similarity, the sensitivity of these two enzymes to their physiological inhibitor, malonyl-CoA, differs greatly (CPT1A has a ten-fold higher Ki for malonyl-CoA) 39,40

doi: 10.1038/nature08778

[DOI] [PubMed] [Google Scholar] 81.Han P., Wang X., Zhou T., Cheng J., Wang C., Sun F., Zhao X
