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The ESI-MS spectrum for Cu 3 -TC-Py provided no evidence of mono- or di-copper(II) complexes forming in tandem with the trinuclear complex

64 reported that in Bacillus megaterium tyrosinase (PDB: 3NM8), the pyranose glucoside part of arbutin faces the metal active site

These findings confirm the successful synthesis and detailed structural characterisation of Compound 1.64 , as shown in Figure 6

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