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Serotonin, dopamine, GABA, and norepinephrine all play roles in mood regulation, and disruptions in any of these systems can produce symptoms of depression or anxiety

whole body oxygen consumption is about 50% of normal (13) whereas brain oxygen consumption can be reduced to about 35% of normal.(14) At very low core temperatures the brain can tolerate more than 30 minutes of circulatory arrest.(15,16) The classic teaching is that CPR must be started promptly and continued without interruption until a return of spontaneous circulation (ROSC) can be established

That overlap is part of why this combination gets discussed so often here

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