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It would be interesting to elucidate the contribution of SLC7A11 to ferroptosis versus other forms of cell death (apoptosis, necrosis, autophagy) following inhibition in a variety of cancers
Also like other phosphonate prodrugs, this strategy was first applied to phosphates to overcome poor cellular uptake, poor conversion to the active component or to release less toxic byproducts [80]
[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Ruan G., Wu F., Shi D., Sun H., Wang F., Xu C
CKD associates with cognitive decline
