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doi: 10.1007/s11064-009-9924-9

5a), a pro-drug that combines sulphapyridine (an antibiotic) and 5-aminosalicylic (an anti-inflammatory agent) linked by an azo bridge, has huge therapeutic potential, but is, unfortunately, labile under physiological conditions (70% degradation by colonic bacteria via azo cleavage
[DOI] [PMC free article] [PubMed] [Google Scholar] Ramaglia V., Hughes T

The good news is that we can increase glutathione levels by supplementation
