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Description
212 In a clinical trial involving 35 individuals with specific MTHFR gene mutations, 1.6 mg of vitamin B 2 per day for 12 weeks lowered homocysteine levels significantly more than placebo and the effect was stronger in those with suboptimal B 2 status

Dosing is extrapolated from preclinical models [1] [6]

It is not an FDA-approved drug and not a legal over-the-counter supplement

Clinical practice and Perfect Bs protocol use a 3-month cycle: a loading phase, a maintenance phase, and a taper, followed by a 2-month break before reassessment
