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The IB degradation product, p65-p50 dimer, translocates to the nucleus and binds to the B site in the BACE1 promoter region, thereby upregulating BACE1 expression (Marwarha et al., 2013)

Most hormones (chemicals made in a gland that travel through the blood stream to have actions in other parts of the body) are related to bone turnover either in positive or negative ways

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Wang Y, Qi H, Liu Y, Duan C, Liu X, Xia T