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Saharan et al
Furthermore, peripheral insulin resistance triggered by uremia, metabolic acidosis and low-grade inflammation is common in CKD (80), leading to intra-portal hyperinsulinemia, but does not necessarily increase hepatic sensitivity to GH because of the reduced hepatic expression of IGF-I and GHR mRNA (81)
Keep a peptide log that records lot numbers, reconstitution dates, and stability observations so that results can be reproduced and anomalies traced back to a specific batch
