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These AHR ligands are expressed on astrocytes and microglia and have been shown to restrain central nervous system inflammation by modulating inflammatory gene programs in glial cells (3234)

The expression of S100A9 in neutrophiles and activated macrophages, cells that produce large amounts of ROS during inflammation, suggests that it protects tissues from oxidative damage (Srikrishna, 2012)

Histological evaluation further showed that the therapeutic efficacy of the probiotic treatment was comparable to that of silver sulfadiazine ointment (308)

Third, the association of nitric oxide metabolism genes with schizophrenia has been revealed (reviewed in [82])