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NAMPT inhibition, reducing NAD levels, thereby decreasing SIRT1 activity, leads to the dramatic elevation of acetylated C/EBP levels and reduces amounts of total C/EBP protein, accompanied by diminished mRNA expression of C/EBP target genes (G-CSF, G-CSFR, and ELANE) (148, 154)

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Archived from the original on January 20, 2021

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Protein expression was quantified by densitometry using the ImageJ software (version 1.47

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