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Introduction Cancer is a major cause of death worldwide, with about 10 million deaths reported in 2020 ( The causal and contributory role of oxidative stress in tumorigenesis has been described previously (Figure 1 depicts antioxidants actions in tumorigenesis and mechanistic pathways

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He was given the antimalarial drug primaquine, and suffered a delayed reaction with kidney pain, dark urine, and low red blood cell counts that led to anaemia and weakness

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Restart at week 17 with protocol adjustments based on lab response

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Studies have shown that oxidative stress promotes brain insulin resistance, and central nervous system (CNS) insulin resistance can affect neuronal development and increase the risk of neurodegenerative diseases (44)

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