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Expression and functional significance of NADPH oxidase 5 (Nox5) and its splice variants in human blood vessels

451 LPA also inhibits type I interferon (IFN I) production and immune responses by dendritic cells, mainly through the LPA-LPAR-PGE2-E-type prostanoid 4 receptor (EP4) axis, which compromises IFN-induced TLR-mediated antitumor immunity

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The PCR protocol began with an initial denaturation step at 94 C for 3 min, followed by 35 cycles including a 1-min denaturation at 94 C, 1-min annealing at 58 C, and 1-min extension at 72 C
