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In the event of a deficiency of this precursor, which is the case with PCS 30,31,32 , the serotonin pathway activated by SSRIs could be regarded as a competitor of the KP

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There are four main types of multiple sclerosis defined according to the disease course: (i) clinically isolated syndrome, (ii) relapsing-remitting multiple sclerosis, (iii) secondary progressive multiple sclerosis, and (iv) primary progressive multiple sclerosis (for more information, visit the National Multiple Sclerosis Society website) (86)