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First, our rescue assays revealed that pSer 727 , but not pTyr 705 , is required for the protective effects of STAT3 against Cd

doi: 10.3389/fragi.2026.1790247 Received 17 January 2026 Revised 27 February 2026 Accepted 20 March 2026 Published 07 April 2026 Volume 7 - 2026 Edited by Filipe Cabreiro, University of Cologne, Germany Reviewed by Wanzi Yao, Peking University, China Updates Copyright 2026 Mavrych, Shypilova and Bolgova

(2014) Figure 4 - Oxidation reaction and electron transporter chain.Source: Flavoprotein-catalyzed oxidations differ from cytochrome P450-catalyzed oxidations in mechanism and in substrate selectivity

Collectively, these findings suggest that PRLMs may delay or attenuate T1DM progression by reducing inflammation and oxidative stress while promoting -cell regeneration
