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21 January 2011
doi: 10.3892/mmr.2024.13162 445 PrasadSTyagiAK

7 In fact, xCT is considered to be the main transporter of cystine in cancer (Table 1) 25,26,27 and its expression is controlled by nuclear factor erythroid 2-related factor 2 (NRF2), a master regulator of the cellular redox state, 28 highlighting the importance of xCT in an oxidative stress-resistant cancer cell phenotype

Annals of Oncology, 25(7), 1328-1333