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The intestinal absorption of heme is thought to occur through two primary mechanisms: receptor-mediated endocytosis and the direct transport of heme by heme carrier protein 1 (HCP1)

Presently, there are a total of four proposed transport models associated with flavonoids, namely glutathione S -transferase (GST), multidrug and toxic compound extrusion (MATE), multidrug resistance-associated protein (MRPs), and bilitranslocase-homolog (BTL)

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