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If methylation is impaired, less homocysteine enters transsulfuration which reduces cysteine production

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[DOI] [PubMed] [Google Scholar] 31.Chandel N.S., Budinger G.R.S., Choe S.H., Schumacker P.T

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The half-life of APAP in the cat is 5 hours, compared to 1.1 hours in the dog, and 2.6 hours in humans.4 Glucuronidation and sulfation are the two major conjugation pathways used by most species to metabolize APAP

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Brain Res 924: 9097, 2002

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