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have shown that treatment with the monoclonal anti-CD38 antibody daratumumab is a promising anti-leukaemic strategy that induces leukemic cell phagocytosis and blocks cell migration [24]
The trade-off is that glucagon agonism is the arm most likely to nudge metabolic parameters in directions that need watching (heart rate and glycemic dynamics among them), which is another reason the documented protocol climbs slowly and why the class monitoring guidance below is not optional context

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