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Spine heads with a greater surface area can accommodate more neurotransmitter receptors and are more likely to form more responsive synapses

Interestingly, the correlation between eGFR and altered cognitive performance, as evidenced by a reduced MMSE score, could be reversed with the addition of homocysteine

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Short-course studies report no overt toxicity at commonly used doses, but programs should include organ-system panels, cardiovascular telemetry where relevant, and pathology review for chronic exposures