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[DOI] [PMC free article] [PubMed] [Google Scholar] 716
In colorectal cancer, IGF-2 secreted by cancer-associated fibroblasts binds to IGF-1R on cancer cells to activate the PI3K/AKT/mTOR and Hippo-YAP1 signaling pathways to promote cancer cell proliferation, migration and invasion
doi: 10.2337/diab.40.4.405
