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It cycles between reduced (GSH) and oxidized (GSSG) forms to preserve cellular oxidative homeostasis

1797) using rubber and bamboo sawdust substrates in tropical regions

To test whether low oxygen tension experienced by retinal cells can stimulate mitophagy, we injected Naive mice or those exposed to OHT (OHT) with pimonidazole, a compound that creates covalent adducts in cells that experience a partial pressure of oxygen lower than 10 mmHg (hypoxia)

For one, it makes a robust clinical trial logistically tricky, said Christopher Milne, past director of research at the Tufts Center for the Study of Drug Development