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A pattern of abnormalities in fatty-acid metabolism characterized by elevations in short-chain and long-chain, but not medium-chain, acyl-carnitines were found in brain tissue of adult rats intracerebroventricularly infused with propionic acid (177)

Plotnikov, et al

When combined with other supplements or taken at higher than recommended doses for several months, some liver and kidney complications have been reported with creatine monohydrate supplementation [32,34]

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