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Sustained hyperglycemia has been shown to affect almost all tissues in the body

Measurement of ROS and Malondialdehyde (MDA) in liver tissues Homogenized liver tissues were mixed with 40 mM Tris-HCl buffer and centrifuged at 12,000 g for 10 min at 4C to obtain supernatant

There is a paucity in the literature of papers addressing molecular mechanisms of new peptide polyagonists and extending these to preclinical and clinical data

Human clinical trials on this specific combination remain limited
