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We perform biopsy first, send the sample for histopathology, and proceed with definitive surgery once the diagnosis is confirmed

Data availability The cryo-EM maps have been deposited in the Electron Microscopy Data Bank (EMDB) under the accession codes EMD-71735 (OCTN2 inward-facing), EMD-71540 (OCTN2 occluded) and EMD-71597 (OCTN2 ipratropium)

Drug Interactions with Direct-Acting Antivirals and Selected Concomitant Medications The education of persons initiating HCV treatment and their caregivers about potential adverse effects of DAA therapy and their management is an integral component of treatment and is important for a successful outcome in all patient populations