epithalon mechanism of action telomerase (also spelled Epitalon or Epithalone) is a synthetic tetrapeptide developed from research into pineal gland extracts, particularly a bovine pineal extract called epithalamin. It was largely pioneered by Russian gerontologist Vladimir Epithalon
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Rayyan software (Ouzzani et al., 2016) was employed for reference management, including the identification and removal of duplicate entries
Occludin, claudin-5, and claudin-8 were found to be downregulated and redistributed, whereas claudin-2 (pore-forming TJ protein) was strongly upregulated

Specifically, we simulate the global temperature response to individual ocean basin SST trends with the Community Earth System Model (CESM1, see Methods)
