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This controlled permeability allows the generation of ionic gradients and results in the compartmentalization of metabolic functions between the cytoplasm and mitochondria

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Another study showed that benfotiamine reduces cerebral oxidative stress associated with diabetes in mice

137 In the paeonol-loaded SLN (PAE-SLN), the disappearance of the characteristic peak of paeonol molecules in the XRD patterns signified the transformation of crystalline drug molecules to an amorphous or molecular state within the lipid matrix