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However, 35 years after the first reports on l-carnitine deficiency in haemodialysis patients, routine l-carnitine supplementation is not recommended by KDIGO or KDOQI clinical guidelines covering several aspects of the renal failure patient, based on lack of definitive evidence of benefit [8, 9, 1214]
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These isoforms are generated by alternative splicing of exons 2, 3, and 10 of its pre-mRNA
