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If the glutathione is broken down into glutamine, glycine, and cysteine, it loses its specific antioxidant structure

Furthermore, other markers including glutathione- S -transferases (GSH), superoxide dismutase, transferrin, catalase, glutathione peroxidase, vitamin A, vitamin B6, vitamin C, cystathionine, iron, zinc, magnesium, ceruloplasmin, total cholesterol, triglycerides, ferritin, and SAM did not significantly associate with ASD (Table 1)

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Finally, to directly assess whether ascites protects against ferroptosis in vivo, we generated GPX4 -knockout, luciferase-expressing CAOV3 cells and injected them intraperitoneally with or without ascites into immunodeficient female mice