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When mutating all but the putative catalytic cysteine (Cys A ) to serines, the remaining Cys21 had a p K a between 6 and 7 (Fig
Concurrently regulating PPAR- and NF-B signaling, the combination intervention offers dual defense against the lipotoxicityinflammationoxidative stress axis that is essential to the pathophysiology of NAFLD
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