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Abstract Riboflavin, known as vitamin B2, a water-soluble vitamin, is an essential nutrient in vertebrates, hence adequate dietary intake is imperative

Although very recently transgenic approaches are one of the probabilistic tools that improve the level of drought tolerance in several plants, such approaches may be achieved only when there is a basic understanding as well as investigation of physio-biochemical mechanism of plants toward drought stress

Its pathophysiology involves diverse mechanisms such as ectopic neuronal discharge, peripheral and central sensitization, dysregulation of ion channels, and disrupted balance between excitatory and inhibitory neurotransmission [43, 44]