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2025;12:e2410630
In general, the reactivity of Michael acceptor influenced by the presence of an electron-withdrawing ester group at C4, an ester vs amide at C2, ring strain (5- versus 6-membered ring) correlated with inhibitor potency
This slimy residue then sticks the bacteria to pipes, pumps, plumbing fixtures, and appliances, causing clogging, foul tastes and odors, corroded pipes and plumbing fixtures, etc
