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Additionally, NK cells promote the upregulation of pro-inflammatory cytokines such as TNF- and IFN- which contributes to neuroinflammation and can exacerbate tissue damage [30]

doi: 10.2165/00003088-197803030-00005

Plateau effect after a certain point, improvement slows or stabilizes, and further gains require more intensive or adjunctive strategies

The intestinal microbiota colonization produces inflammatory metabolites, which establishes the way for carcinogenesis
